Article
Manipulation of catechol-O-methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: a hypothesis.
Medical hypotheses - 1 Jan 2007
Blum Kenneth, Chen Thomas J H, Meshkin Brian, Waite Roger L, Downs B William, Blum Seth H, Mengucci Julie F, Arcuri Vanessa, Braverman Eric R, Palomo Tomas
Abstract excerpt
There are common genetic mechanisms responsible for both drug effects and subsequent seeking behavior. In 1996, we coined the term Reward Deficiency Syndrome (RDS). Past and current treatment of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is considered by most to be...
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