Article
p16(CDKN2) gene polymorphism: association with histologic subtypes of epithelial ovarian cancer in China.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Yan L, Na W, Shan K, Xiao-Wei M, Wei G, Shu-Cheng C
Abstract excerpt
p16 is an important tumor suppressor gene, which is inactivated in many kinds of tumors. The common variants of p16 may be associated with the risk of certain tumors development. We analyzed the frequency of two adjacent polymorphisms in p16 exon 3 (540C-->G and 580C-->T) and their haplotype in blood samples from epithelial ovarian cancer (EOC) patients and healthy controls using polymerase chain...
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