Article
Cwp2p, the plasma membrane receptor for Pichia membranifaciens killer toxin.
Molecular microbiology - 1 May 2007
Santos Antonio, San Mauro Manuel, Abrusci Concepción, Marquina Domingo
Abstract excerpt
PMKT is a channel-forming killer toxin secreted by Pichia membranifaciens. To identify novel genes that mediate cellular resistance to PMKT we screened a collection of 288 deletion mutants. We found 29 open reading frames (ORFs) that, when deleted, confer resistance to PMKT. In addition, the deletion of 15 ORFs was observed to increase protoplast resistance, in agreement with the initial assumption that a plasma...
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