Article
P-type ATPase spf1 mutants show a novel resistance mechanism for the killer toxin SMKT.
Molecular microbiology - 1 May 1999
Suzuki C, Shimma Y I
Abstract excerpt
SMKT, a killer toxin produced by the halotolerant yeast Pichia farinosa KK1, consists of alpha and beta subunits with folding remarkably similar to that of the fungal killer toxin KP4, a Ca2+ channel inhibitor. The budding yeast Saccharomyces cerevisiae is sensitive to SMKT. To understand the killing mechanism of SMKT, we isolated SMKT-resistant mutants of S. cerevisiae and characterized them. Five spf mutants...
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