Article
Hepatitis C virus genotyping using an oligonucleotide microarray based on the NS5B sequence.
Journal of clinical microbiology - 1 Nov 2010
Gryadunov Dimitry, Nicot Florence, Dubois Martine, Mikhailovich Vladimir, Zasedatelev Alexander, Izopet Jacques
Abstract excerpt
The genotype of the hepatitis C virus (HCV) is essential for determining treatment duration in clinical practice and for epidemiological and clinical studies. Currently, few genotyping assays that determine the HCV subtype are available. This report describes a microarray-based molecular technique for identifying the HCV genotype and subtype. It uses low-density hydrogel-based biochips containing genotype- and...
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