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Article

The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.

Annals of the New York Academy of Sciences - 1 Apr 2007

Davis Terence, Wyllie Fiona S, Rokicki Michal J, Bagley Mark C, Kipling David

Abstract excerpt

Werner syndrome (WS) is a premature aging disorder used as a model of normal human aging. WS individuals have several characteristics of normal aging, such as cataracts, hair graying, and skin aging, but manifest these at an early age. Additionally, WS individuals have high levels of inflammatory diseases, such as atherosclerosis and type 2 diabetes. The in vivo aging in WS is associated with accelerated aging of...

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PMID: 17460211
DOI: 10.1196/annals.1395.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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