Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Werner Syndrome as an example of inflamm-aging: possible therapeutic opportunities for a progeroid syndrome?

Rejuvenation research - 1 Jan 2006

Davis Terence, Kipling David

Abstract excerpt

Werner syndrome (WS) is a premature aging disorder that is widely used as a model for some aspects of the normal human aging process. Individuals with WS have several of the characteristics of normal aging, such as cataracts, hair graying, and skin aging, but manifest these at an early age. In addition, WS is associated with high levels of inflammatory diseases such as atherosclerosis and type II diabetes. Recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Exodeoxyribonucleases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Imidazoles

Share to Intercellular Adhesion Molecule-1

Share to p38 Mitogen-Activated Protein Kinases

Share to RecQ Helicases

Share to Werner Syndrome

Share to Werner Syndrome Helicase

Source

Identifiers

PMID: 16859481
DOI: 10.1089/rej.2006.9.402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Werner Syndrome as an example of inflamm-aging: possible therapeutic opportunities for a progeroid syndrome?PMID 16859481Read ↗

The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.Semantic proximity Read ↗

A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review).Semantic proximity Read ↗

Vitamin C alleviates aging defects in a stem cell model for Werner syndromeSemantic proximity Read ↗

Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseasesSemantic proximity Read ↗

Recent Advances in Understanding Werner SyndromeSemantic proximity Read ↗

NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal modelSemantic proximity Read ↗

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.Semantic proximity Read ↗

Human pluripotent stem cell-based models suggest preadipocyte senescence as a possible cause of metabolic complications of Werner and Bloom SyndromesSemantic proximity Read ↗

A case of Werner syndrome without metabolic abnormality: implications for the early pathophysiology.Semantic proximity Read ↗

Pathophysiology of premature aging characteristics in Mendelian progeroid disorders.Semantic proximity Read ↗

The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responsesSemantic proximity Read ↗

What can progeroid syndromes tell us about human aging?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.