Article
Genetic and phenotypic features of blood and genital viral populations of clinically asymptomatic and antiretroviral-treatment-naive clade a human immunodeficiency virus type 1-infected women.
Journal of clinical microbiology - 1 Jun 2007
Andreoletti Laurent, Skrabal Katharina, Perrin Virginie, Chomont Nicolas, Saragosti Sentob, Gresenguet Gerard, Moret Helene, Jacques Jerome, Longo Jean de Dieu, Matta Mathieu, Mammano Fabrizio, Belec Laurent
Abstract excerpt
In the present study, we assessed whether human immunodeficiency virus type 1 (HIV-1) genetic compartmentalization was associated with phenotypic CCR5 (R5) or CXCR4 (X4) coreceptor usage differences between the systemic and the genital viral populations. Four clinically asymptomatic and treatment-naïve clade A HIV-1-infected patients were selected from a cohort of 274 African women, because they were free of all...
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