Article
Functional analysis of two isoforms of phosphatidylethanolamine N-methyltransferase.
The Biochemical journal - 1 Dec 2010
Morita Shin-ya, Takeuchi Atsuko, Kitagawa Shuji
Abstract excerpt
The enzyme catalysing the conversion of PE (phosphatidylethanolamine) into PC (phosphatidylcholine), PEMT (PE N-methyltransferase), exists as two isoforms, PEMT-L (longer isoform of PEMT) and PEMT-S (shorter isoform of PEMT). In the present study, to compare the functions of the two isoforms of PEMT, we established HEK (human embryonic kidney)-293 cell lines stably expressing PEMT-L and PEMT-S. Both PEMT-L and...
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