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Article

Regenerative lesions in ulcerative colitis are characterized by microsatellite mutation.

Genes, chromosomes & cancer - 1 Jul 1997

Heinen C D, Noffsinger A E, Belli J, Straughen J, Fischer J, Groden J, Fenoglio-Preiser C M

Abstract excerpt

An increased risk of colon cancer has been observed in individuals with long-standing ulcerative colitis (UC). In order to identify molecular genetic markers for the development of neoplasia in UC individuals, we isolated DNA from normal, regenerative, and dysplastic mucosa, as well as from colon carcinomas from UC patients, and evaluated it for the presence of mutations in microsatellite DNA sequences. DNAs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9218998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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