Article
Analysis of genomic instability in adult-onset celiac disease patients by microsatellite instability and loss of heterozygosis.
European journal of gastroenterology & hepatology - 1 Dec 2008
Fundia Ariela F, Cottliar Alejandra S, La Motta Graciela, Crivelli Adriana, Gómez Juan Carlos, Slavutsky Irma R, Larripa Irene B
Abstract excerpt
BACKGROUND AND AIMS: Malignant complications of celiac disease (CD) include carcinomas and lymphomas. The genetic basis behind cancer development in CD is not known, but acquisition of genetic abnormalities and genomic instability has been involved. The aim of this study was to explore molecular characteristics of genomic instability in CD patients by analyzing microsatellite instability (MSI) and loss of...
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