Article
Pemphigus: etiology, pathogenesis, and inducing or triggering factors: facts and controversies.
Clinics in dermatology - 1 Jan 2000
Ruocco Vincenzo, Ruocco Eleonora, Lo Schiavo Ada, Brunetti Giampiero, Guerrera Luigi Pio, Wolf Ronni
Abstract excerpt
Pemphigus includes a group of autoimmune bullous diseases with intraepithelial lesions involving the skin and Malpighian mucous membranes. Pemphigus vulgaris (PV), the most frequent and representative form of the group, is a prototypical organ-specific human autoimmune disorder with a poor prognosis in the absence of medical treatment. The pathomechanism of PV hinges on autoantibodies damaging cell-cell cohesion...
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