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Article

Oestrogen receptor alpha gene polymorphism associates with occurrence of graft-versus-host disease and reduced survival in HLA-matched sib-allo BMT.

Bone marrow transplantation - 1 Jul 2003

Middleton P G, Norden J, Cullup H, Cavet J, Jackson G H, Taylor P R A, Dickinson A M

Abstract excerpt

Oestrogen receptors mediate the cellular response to oestrogens and related compounds and promote a wide range of effects on haemopoiesis. Polymorphisms of the oestrogen receptor genes have previously been associated with variation in bone mineral density, likelihood of fractures, risk of developing Alzheimer's disease, endometrial cancer and response to hormone replacement therapy. We examined the polymorphisms...

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Identifiers

PMID: 12815477
DOI: 10.1038/sj.bmt.1704090

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