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Article

B7 and 34B7 monoclonal antibodies: a theoretical approach to the molecular basis of immunoglobulin cross-reactive antibodies.

Hybridoma (2005) - 1 Apr 2007

Hernández Tays, López-Requena Alejandro, De Acosta Cristina Mateo, Mustelier Geraudis, Roque-Navarro Lourdes, Pérez Rolando

Abstract excerpt

Neonatal natural antibodies (NAbs) are characterized by their high degree of idiotypic cross reactivity, together with some restrictions in the genetic mechanisms of variable region diversity. We report here the immunogenetic analysis of two anti-idiotype antibodies (B7 and 34B7 monoclonal antibodies [MAbs]), which are also polyreactive as NAbs. Evidence of a process of somatic mutations were found for heavy and...

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Source

Identifiers

PMID: 17451353
DOI: 10.1089/hyb.2006.0051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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