Article
Lack of association of CPT1A polymorphisms or haplotypes on hepatic lipid content or insulin resistance in Japanese individuals with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 May 2007
Hirota Yushi, Ohara Takeshi, Zenibayashi Masako, Kuno Shin-ichi, Fukuyama Keiko, Teranishi Tetsuya, Kouyama Kunichi, Miyake Kazuaki, Maeda Eiichi, Kasuga Masato
Abstract excerpt
Accumulation of fat in the liver is associated with insulin resistance and type 2 diabetes mellitus. The carnitine palmitoyltransferase (CPT) enzyme system facilitates the transport of long-chain fatty acids into mitochondria, and the gene for the hepatic isoform of CPT1 (CPT1A) is a candidate ge...
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