Article
Fat distribution, lipid accumulation in the liver, and exercise capacity do not explain the insulin resistance in healthy males with a family history for type 2 diabetes.
The Journal of clinical endocrinology and metabolism - 1 Sept 2003
Johanson Else H, Jansson Per-Anders, Lönn Lars, Matsuzawa Yuji, Funahashi Tohru, Taskinen Marja-Riitta, Smith Ulf, Axelsen Mette
Abstract excerpt
To explore the mechanisms for the insulin resistance associated with a family history of type 2 diabetes, we studied 16 healthy men with at least two first-degree relatives with type 2 diabetes and 16 control subjects without known heredity. They were pair-wise matched for age, body mass index, and fasting triglycerides and underwent an oral glucose tolerance test, iv glucose infusion to measure the early insulin...
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