Article
Association of the -112A>C polymorphism of the uncoupling protein 1 gene with insulin resistance in Japanese individuals with type 2 diabetes.
Biochemical and biophysical research communications - 27 Jan 2006
Fukuyama Keiko, Ohara Takeshi, Hirota Yushi, Maeda Kengo, Kuno Shin-ichi, Zenibayashi Masako, Teranishi Tetsuya, Kouyama Kunichi, Maeda Eiichi, Sakamoto Norihiro, Kasuga Masato
Abstract excerpt
The -112A>C polymorphism (rs10011540) of the gene for uncoupling protein 1 (UCP1) has been associated with type 2 diabetes mellitus in Japanese individuals. The aim of the present study was to investigate the effects of this polymorphism, as well as the well-known -3826A>G polymorphism (rs1800592), on clinical characteristics of type 2 diabetes. We determined the genotypes of the two polymorphisms in 93 Japanese...
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