Article
Modelling KIR-HLA genotype disparities in type 1 diabetes.
Tissue antigens - 1 Apr 2007
van der Slik A R, Alizadeh B Z, Koeleman B P C, Roep B O, Giphart M J
Abstract excerpt
We previously reported that a disparate distribution between killer cell immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA) class 1 genes is associated with susceptibility to develop type 1 diabetes. Here we compare multiple models which reflect the combined genotype effects of combinations of functional inhibitory and activating KIRs in relation to HLA in an extended cohort of patients with...
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