Article
Association of Trp64Arg polymorphism of beta3-adrenergic receptor with insulin resistance in Polish children with obesity.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Feb 2008
Zawodniak-Szałapska Małgorzata, Stawerska Renata, Brzeziańska Ewa, Pastuszak-Lewandoska Dorota, Lukamowicz Jolanta, Cypryk Katarzyna, Lewiński Andrzej
Abstract excerpt
AIM: To establish the influence of the Trp64Arg variant of the beta3-adrenergic receptor (Trp64Arg- beta3AR) on body mass index (BMI) and insulin resistance (IR) in obese children. METHODS: BMI, presence of the Trp64Arg mutation, plasma glucose and insulin concentrations during an oral glucose tolerance test (OGTT) and IR were determined in 60 obese and 33 normal weight children. RESULTS: The frequency of...
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