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Article

Association between rs4994 variant in β3-Adrenergic receptor and obesity in Vietnamese preschool-age children, independent of eating behaviors.

BMC pediatrics - 18 Sept 2024

Hanh Nguyen Thi Hong, Trang Do Thi Nhu, Thu Nguyen Thi Trung, Tuyet Le Thi

Abstract excerpt

BACKGROUND: The Arg64 allele of the rs4994 (Trp64Arg) variant in the β3-adrenergic receptor (ADRB3) gene is involved in the control of energy balance by altering lipolysis and thermogenesis in adipocytes, ultimately contributing to the development of obesity. The objective of our study was to investigate the association between the rs4994 variant of the ADRB3 gene and obesity in Hanoi preschool-age children,...

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Identifiers

PMID: 39294633
DOI: 10.1186/s12887-024-05073-7
PMCID: PMC11409677

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