Article
Aberrant over-expression of a forkhead family member, FOXO1A, in a brain tumor cell line.
BMC cancer - 19 Apr 2007
Dallas Peter B, Egli Simone, Terry Philippa A, Kees Ursula R
Abstract excerpt
BACKGROUND: The mammalian FOXO (forkhead box, O subclass) proteins are a family of pleiotropic transcription factors involved in the regulation of a broad range of cellular processes critical for survival. Despite the essential and diverse roles of the FOXO family members in human cells and their involvement in tumor pathogenesis, the regulation of FOXO expression remains poorly understood. We have addressed the...
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