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Article

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.

The Journal of biological chemistry - 19 Sept 2003

Jacobs Frank M J, van der Heide Lars P, Wijchers Patrick J E C, Burbach J Peter H, Hoekman Marco F M, Smidt Marten P

Abstract excerpt

Forkhead transcription factors of the FoxO-group are associated with cellular processes like cell cycle progression and DNA-repair. FoxO function is regulated by protein kinase B (PKB) via the phosphatidylinositol 3-kinase/PKB survival pathway. Phosphorylation of serine and threonine residues in specific PKB phosphorylation motifs leads to exclusion of FoxO-proteins from the nucleus, which excludes them from...

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Source

Identifiers

PMID: 12857750
DOI: 10.1074/jbc.M302804200

Genes

FOXO6

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Click a neighbor to travelStep 1 · 12 closest

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.PMID 12857750Read ↗

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FoxO transcription factors in oxidative stress response and ageing – a new fork on the way to longevity?Semantic proximity Read ↗

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Re-evaluating the role of FOXOs in cancerSemantic proximity Read ↗

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FOXO transcription factors in cancer development and therapy.Semantic proximity Read ↗

Applications of post-translational modifications of FoxO family proteins in biological functionsSemantic proximity Read ↗

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