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Article

Preimplantation genetic haplotyping: 127 diagnostic cycles demonstrating a robust, efficient alternative to direct mutation testing on single cells.

Reproductive biomedicine online - 1 Apr 2010

Renwick Pamela, Trussler Jane, Lashwood Alison, Braude Peter, Ogilvie Caroline Mackie

Abstract excerpt

Preimplantation genetic diagnosis using whole genome amplification and a haplotyping approach (PGH) was first described in 2006 and suggested as an efficient alternative to single-cell PCR for monogenic disorders. DNA from single cells was amplified using multiple displacement amplification; the...

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Identifiers

PMID: 20144563
DOI: 10.1016/j.rbmo.2010.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20144563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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