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Article

Reliable gender screening for human preimplantation embryos, using multiple DNA target-sequences

1 Oct 1992

Abstract excerpt

Dependable methods were developed for preimplantation sexing of human IVF embryos, for use in clinical settings where prospective parents are at high risk for transmission of X-linked diseases. Using single cultured cells and blastomeres from human embryos as model systems, a multiplex protocol was developed for rapid analysis via nested polymerase chain reaction (PCR). Reliability was enhanced by...

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PMID: 1479016
DOI: 10.1093/oxfordjournals.humrep.a137846

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