Article
Multiple displacement amplification on single cell and possible PGD applications.
Molecular human reproduction - 1 Nov 2004
Hellani Ali, Coskun Serdar, Benkhalifa Moncef, Tbakhi Abelghani, Sakati Nadia, Al-Odaib Ali, Ozand Pinar
Abstract excerpt
Multiple displacement amplification (MDA) is a technique used in the amplification of very low amounts of DNA and reported to yield large quantities of high-quality DNA. We used MDA to amplify the whole genome directly from a single cell. The most common techniques used in PGD are PCR and fluorescent in-situ hybridization (FISH). There are many limitations to these techniques including, the number of chromosomes...
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