Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides.

doi:10.1007/BF02173204

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Article

Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides.

Molecular & general genetics : MGG - 27 Aug 1996

Williamson M S, Martinez-Torres D, Hick C A, Devonshire A L

Abstract excerpt

We report the isolation of cDNA clones containing the full 6.3-kb coding sequence of the para-type sodium channel gene of the housefly, Musca domestica. This gene has been implicated as the site of knockdown resistance (kdr), an important resistance mechanism that confers nerve insensitivity to D...

Topics

Amino Acid Sequence
Animals
Binding Sites
Cloning, Molecular
DDT
Genes, Insect
Houseflies
Insecticide Resistance
Insecticides
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Pyrethrins
RNA Splicing
Sequence Alignment
Sequence Analysis
Sodium Channels

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Open in PubMed

Identifiers

PMID: 8804403
DOI: 10.1007/BF02173204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8804403-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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