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Discovery and Validation of 3 Novel DNA Methylation Markers of Prostate Cancer Prognosis

15 Apr 2007

Abstract excerpt

PURPOSE: About 15% of men experience prostate specific antigen recurrence after radical prostatectomy. A DNA methylation based molecular test could provide important information to predict which patients are most likely to experience recurrence. MATERIALS AND METHODS: We performed a genome-wide scan to find aberrantly methylated loci in prostate cancer from patients with early recurrence, high Gleason score or...

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PMID: 17437806
DOI: 10.1016/j.juro.2007.01.010

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