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Article

Validation Study of Genes with Hypermethylated Promoter Regions Associated with Prostate Cancer Recurrence

10 Apr 2014

Abstract excerpt

BACKGROUND: One challenge in prostate cancer is distinguishing indolent from aggressive disease at diagnosis. DNA promoter hypermethylation is a frequent epigenetic event in prostate cancer, but few studies of DNA methylation in relation to features of more aggressive tumors or prostate cancer recurrence have been completed. METHODS: We used the Infinium HumanMethylation450 BeadChip to assess DNA methylation in...

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PMID: 24718283
DOI: 10.1158/1055-9965.epi-13-1000

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