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CD44 and PTGS2 Methylation are Independent Prognostic Markers for Biochemical Recurrence Among Prostate Cancer Patients with Clinically Localized Disease

23 Oct 2006

Abstract excerpt

Up to 30% of men with clinically localized disease who receive radical prostatectomy develop a biochemical recurrence. Gene methylation in tumor tissue may distinguish men with aggressive cancer. This study evaluated methylation of GSTP1, RARb2, CD44 and PTGS2 with biochemical recurrence among 60 patients who underwent radical prostatectomy using logistic regression and Kaplan Meier time to event analysis....

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Share to Epigenetics and DNA Methylation
Share to Glutathione Transferases and Polymorphisms
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PMID: 17998819
DOI: 10.4161/epi.1.4.3530

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