Article
C-reactive protein is directly related to plasminogen activator inhibitor type 1 (PAI-1) levels in diabetic subjects with the 4G allele at position -675 of the PAI-1 gene.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Mar 2008
Testa R, Bonfigli A R, Sirolla C, Marra M, Boemi M, Mari D, Sacchi E, Dolci A, Catalano A, Procopio A, Ceriello A
Abstract excerpt
BACKGROUND AND AIMS: C-reactive protein (CRP) has been identified as a possible factor able to promote atherosclerosis. "In vitro" studies have demonstrated that CRP induces plasminogen activator inhibitor type 1 (PAI-1) expression, suggesting a hypofibrinolytic role for CRP. As CRP and PAI-1 lev...
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