Article
[Association between human papillomavirus (HPV) type 16 infection and E6/E7 gene variant and the cervical lesions in Beijing].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Mar 2007
Yang Ying-jie, Zhao Jian, Liao Qin-ping
Abstract excerpt
OBJECTIVE: To investigate the association between HPV16 infection, E6/E7 variations and the cervical lesions. METHODS: HPV subtypes were detected by using flow-through hybridization technique, E6/E7 gene was extracted from cervical lesions in 80 patients with HPV16 infection, PCR amplified, cloned into plasmid pMD18-T and sequenced. RESULTS: HPV 16 was the most common type which accounted for 33.3% (154/463), the...
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