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Apolipoprotein E epsilon4 genotype is independently associated with increased intima-media thickness in a recessive pattern.

Lipids - 1 May 2007

Wohlin M, Sundström J, Lannfelt Lars, Axelsson Tomas, Syvänen A C, Andrén B, Basu S, Lind L

Abstract excerpt

Polymorphisms in the apolipoprotein E (Apo E) gene have been associated with lipid levels, carotid intima media thickness (CCA-IMT), inflammation and cardiovascular disease (CVD). Earlier findings suggested an association of the Apo E alleles with increased CCA-IMT following a recessive pattern. Whether associations might be independent of C-reactive protein (CRP), lipid levels and other CVD risk factors is not...

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PMID: 17426996
DOI: 10.1007/s11745-007-3045-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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