Article
Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction.
Clinical chemistry - 1 Dec 2000
Batalla A, Alvarez R, Reguero J R, Hevia S, Iglesias-Cubero G, Alvarez V, Cortina A, González P, Celada M M, Medina A, Coto E
Abstract excerpt
BACKGROUND: Several studies based on different populations worldwide have described an association between cardiovascular diseases and genetic variations in the apolipoprotein E (A:POE), angiotensinogen (A:GT), angiotensin receptor type 1 (A:T1R), and angiotensin-converting enzyme (A:CE) genes. In addition, there is growing evidence of an interaction between hypercholesterolemia and the renin-angiotensin system...
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