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Article

MAP17 overexpression is a common characteristic of carcinomas

9 Apr 2007

Abstract excerpt

We undertook a large-scale genetic screen to identify genes able to alter the cellular response to physiological signals and provide selective advantage once tumorigenesis has begun. We identified MAP17, a small 17 kDa non-glycosylated membrane protein previously identified, being overexpressed in carcinomas. We found that MAP17 is overexpressed in a great variety of human carcinomas. Immunohistochemical analysis...

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PMID: 17426052
DOI: 10.1093/carcin/bgm083

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