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Article

The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells

14 Aug 2013

Abstract excerpt

BACKGROUND: In eukaryotes, miR-16 is an important microRNA (miRNA) that is involved in numerous biological processes. However, it is not fully understood how miR-16 executes its physiological functions. In the present study, we aimed to identify novel miR-16 targets and study their biological functions. METHODS: Candidate target genes of miR-16 were screened by microarray analysis of mRNA levels in several cancer...

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PMID: 23941513
DOI: 10.1186/1476-4598-12-92

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