Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice.

Neuroscience letters - 17 May 2007

Huang Qing-Yuan, Yu Liqun, Ferrante Robert J, Chen Jiang-Fan

Abstract excerpt

3-Nitropropionic acid (3-NP), an irreversible inhibitor of succinate dehydrogenase, produces selective lesions in striatal neurons that resemble those observed in Huntington's disease neuropathology. In this study, we evaluated the role of peripheral bone marrow-derived cells (BMDCs) in the 3-NP-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corpus Striatum
Share to Injections, Intraperitoneal
Share to Nerve Degeneration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurotoxins

Share to Nitro Compounds

Share to Propionates

Share to Superoxide Dismutase-1

Share to Transplantation Chimera

Source

Identifiers

PMID: 17418947
DOI: 10.1016/j.neulet.2007.03.038

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17418947-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice.PMID 17418947Read ↗

The Striatum Is the Most Vulnerable Region in the Brain to Mitochondrial Energy Compromise: A Hypothesis to Explain Its Specific VulnerabilitySemantic proximity Read ↗

3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.Semantic proximity Read ↗

A dual role of adenosine A2A receptors in 3-nitropropionic acid-induced striatal lesions: implications for the neuroprotective potential of A2A antagonists.Semantic proximity Read ↗

Adult olfactory bulb neural precursor cell grafts provide temporary protection from motor neuron degeneration, improve motor function, and extend survival in amyotrophic lateral sclerosis mice.Semantic proximity Read ↗

Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype.Semantic proximity Read ↗

Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Mice transgenic for the Huntington's disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity.Semantic proximity Read ↗

Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response.Semantic proximity Read ↗

Reduced mitochondrial complex II activity enhances cell death via intracellular reactive oxygen species in STHdhQ111 striatal neurons with mutant huntingtin.Semantic proximity Read ↗

Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues.Semantic proximity Read ↗

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.