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Article

Catechol-o-methyltransferase polymorphism and susceptibility to major depressive disorder modulates psychological stress response.

Psychiatric genetics - 1 Jun 2007

Jabbi Mbemba, Kema Ido P, van der Pompe Gieta, te Meerman Gerard J, Ormel Johan, den Boer Johan A

Abstract excerpt

OBJECTIVES: The stress response is related to both physiological and psychological factors and is strongly marked by a neuroendocrine component. Genetic factors are believed to underlie individual differences in the degree of stress resilience and thereby contribute in determining susceptibility to stress-related pathologies like major depressive disorder (MDD). Little, however, is known about the genetic...

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PMID: 17417063
DOI: 10.1097/YPG.0b013e32808374df

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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