Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Levels of extra domain A containing fibronectin in human atherosclerotic plaques are associated with a stable plaque phenotype.

Atherosclerosis - 1 Nov 2007

van Keulen J Karlijn, de Kleijn Dominique P, Nijhuis Manon M Oude, Busser Els, Velema Evelyn, Fijnheer Rob, van der Graaf Yolanda, Moll Frans L, de Vries Jean Paul, Pasterkamp Gerard

Abstract excerpt

BACKGROUND: Extra domain A (EDA), splice-variant of fibronectin, is a Toll-like receptor 4 (Tlr4) ligand. Recently, EDA has been demonstrated to enhance atherogenesis in mice but human data on the role of EDA in atherosclerotic disease are lacking. We hypothesized that EDA is associated with unst...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteries
Share to Atherosclerosis
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibronectins

Share to Mammary Glands, Human

Share to Matrix Metalloproteinases

Share to Protein Structure, Tertiary

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 17416372
DOI: 10.1016/j.atherosclerosis.2007.03.014

Genes

EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17416372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Levels of extra domain A containing fibronectin in human atherosclerotic plaques are associated with a stable plaque phenotype.PMID 17416372Read ↗

Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.Semantic proximity Read ↗

Differential Roles of Endothelial Cell-Derived and Smooth Muscle Cell-Derived Fibronectin Containing Extra Domain A in Early and Late AtherosclerosisSemantic proximity Read ↗

Athero-express: differential atherosclerotic plaque expression of mRNA and protein in relation to cardiovascular events and patient characteristics. Rationale and design.Semantic proximity Read ↗

Gender-associated differences in plaque phenotype of patients undergoing carotid endarterectomy.Semantic proximity Read ↗

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaquesSemantic proximity Read ↗

Syndecan-1 as a predictor of vulnerable atherosclerotic plaquesSemantic proximity Read ↗

Increased expression of the transforming growth factor-beta signaling pathway, endoglin, and early growth response-1 in stable plaques.Semantic proximity Read ↗

Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis.Semantic proximity Read ↗

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.Semantic proximity Read ↗

Plasma C-reactive protein is associated with a pro-inflammatory and adverse plaque phenotype.Semantic proximity Read ↗

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E.Semantic proximity Read ↗

Proteomics and ex vivo plaque culture identify the insulin-like growth factor axis as a potential regulator of matrix remodelling in carotid plaques.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.