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Article

Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis.

Atherosclerosis - 1 Feb 2017

Lunde Ngoc Nguyen, Holm Sverre, Dahl Tuva B, Elyouncha Inass, Sporsheim Bjørnar, Gregersen Ida, Abbas Azhar, Skjelland Mona, Espevik Terje, Solberg Rigmor, Johansen Harald Thidemann, Halvorsen Bente

Abstract excerpt

BACKGROUND AND AIMS: The cysteine protease legumain has been shown to be up-regulated in unstable atherosclerotic plaques. This study aims to further elucidate legumain in atherosclerosis, by examining legumain in plasma and carotid plaques from patients with carotid stenosis. Furthermore, legumain secretion from monocyte-derived macrophages treated with atherogenic lipids during macrophage polarization was...

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Share to Carotid Arteries
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27940038
DOI: 10.1016/j.atherosclerosis.2016.11.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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