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Article

Expression of oncofetal RNA‐binding protein CRD‐BP/IMP1 predicts clinical outcome in colon cancer

5 Apr 2007

Abstract excerpt

The oncofetal CRD-BP/IMP1 RNA binding protein regulates posttranscriptionally a handful of RNA transcripts, implicated in cell adhesion and invadopodia formation and was recently identified as a target of the beta-catenin/Tcf transcription factor that is constitutively activated in colorectal carcinomas (CRCs). The expression of CRD-BP/IMP1 was studied in normal adult intestines and CRCs. In normal mucosa,...

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PMID: 17415713
DOI: 10.1002/ijc.22716

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