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Article

IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts.

Carcinogenesis - 1 Nov 2013

Hamilton Kathryn E, Noubissi Felicite K, Katti Prateek S, Hahn Christopher M, Davey Sonya R, Lundsmith Emma T, Klein-Szanto Andres J, Rhim Andrew D, Spiegelman Vladimir S, Rustgi Anil K

Abstract excerpt

Igf2 mRNA binding protein 1 (IMP1, CRD-BP, ZBP-1) is a messenger RNA binding protein that we have shown previously to regulate colorectal cancer (CRC) cell growth in vitro. Furthermore, increased IMP1 expression correlates with enhanced metastasis and poor prognosis in CRC patients. In the curren...

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Identifiers

PMID: 23764754
DOI: 10.1093/carcin/bgt217
PMCID: PMC3810836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23764754-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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