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Article

Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2012

Lochhead Paul, Imamura Yu, Morikawa Teppei, Kuchiba Aya, Yamauchi Mai, Liao Xiaoyun, Qian Zhi Rong, Nishihara Reiko, Wu Kana, Meyerhardt Jeffrey A, Fuchs Charles S, Ogino Shuji

Abstract excerpt

BACKGROUND: Evidence suggests that insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3, also known as IMP3) represents a promising cancer biomarker. However, the clinical, pathological, molecular and prognostic features of IGF2BP3-positive colorectal cancers remain uncertain. MATERIALS AND METHODS: We evaluated IGF2BP3 expression by immunohistochemistry in 671 rectal and colon cancer cases that...

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Identifiers

PMID: 22840368
DOI: 10.1016/j.ejca.2012.06.021
PMCID: PMC3613860

Genes

BRAF
IMP3
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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