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Article

Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database.

BMC infectious diseases - 27 Feb 2008

Ruelle Jean, Roman François, Vandenbroucke Anne-Thérèse, Lambert Christine, Fransen Katrien, Echahidi Fedoua, Piérard Denis, Verhofstede Chris, Van Laethem Kristel, Delforge Marie-Luce, Vaira Dolorès, Schmit Jean-Claude, Goubau Patrick

Abstract excerpt

BACKGROUND: Guidelines established for the treatment of HIV-1 infection and genotype interpretation do not apply for HIV-2. Data about antiretroviral (ARV) drug efficacy and resistance mutations is scarce. METHODS: Clinical data about HIV-2 infected patients in Belgium and Luxembourg were collected and the effect of ARV therapy on plasma viral load and CD4 counts were analysed. Viral RNA encoding for protease...

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Identifiers

PMID: 18304321
DOI: 10.1186/1471-2334-8-21
PMCID: PMC2292191

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Source receipt: pubmed, retrieved 7 Sept 2026.

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