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Article

Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2007

Krönke Gerhard, Kadl Alexandra, Ikonomu Elena, Blüml Stefan, Fürnkranz Alexander, Sarembock Ian J, Bochkov Valery N, Exner Markus, Binder Bernd R, Leitinger Norbert

Abstract excerpt

OBJECTIVE: Activation of peroxisome proliferator-activated receptors (PPARs) by lipid-lowering fibrates and insulin-sensitizing thiazolidinediones inhibits vascular inflammation, atherosclerosis, and restenosis. Here we investigate if the vasculoprotective and anti-inflammatory enzyme heme oxygenase-1 (HO-1) is regulated by PPAR ligands in vascular cells. METHODS AND RESULTS: We show that treatment of human...

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PMID: 17413033
DOI: 10.1161/ATVBAHA.107.142638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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