Decreased risk of ovarian cancer associated with rs9898876 sex hormone-binding globulin gene variant.

doi:10.1007/s11033-022-07297-1

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Article

Decreased risk of ovarian cancer associated with rs9898876 sex hormone-binding globulin gene variant.

Molecular biology reports - 1 Jun 2022

Zidi Sabrina, Stayoussef Mouna, Sontini Feryel K, Mezlini Amel, Yacoubi-Loueslati Besma, Almawi Wassim Y

Abstract excerpt

BACKGROUND: Ovarian cancer (OC) is one of the most common gynecologic cancers,with significant morbidity and mortality. The risk of OC is influenced by hormone status, of which sex hormone-binding globulin (SHBG), which influences the serum availability of steroid sex hormones, is implicated in the pathogenesis and evolution of OC. The aim of this study is to evaluate the involvement of common SHBG gene variants...

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PMID: 35277784
DOI: 10.1007/s11033-022-07297-1

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