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Article

Genetic polymorphisms associated with priapism in sickle cell disease.

British journal of haematology - 1 May 2007

Elliott Laine, Ashley-Koch Allison E, De Castro Laura, Jonassaint Jude, Price Jennifer, Ataga Kenneth I, Levesque Marc C, Brice Weinberg J, Eckman James R, Orringer Eugene P, Vance Jeffery M, Telen Marilyn J

Abstract excerpt

Priapism occurs in 30-45% of male patients with sickle cell disease (SCD), but the possible influence of genetic risk factors on the incidence of priapism is not well understood. We examined genetic polymorphisms in 199 unrelated, adult (>18 years), male patients with Hb SS and Hb Sbeta(0)-thalassaemia, 83 (42%) of whom reported a history of priapism. Candidate genes for association with priapism were identified...

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Source

Identifiers

PMID: 17408468
DOI: 10.1111/j.1365-2141.2007.06560.x

Genes

AQP1
ITGAV
TGFBR3
NOS2
NOS3
SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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