Article
Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia.
British journal of haematology - 1 Jan 2005
Nolan Vikki G, Baldwin Clinton, Ma Qianli, Wyszynski Diego F, Amirault Yvonne, Farrell John J, Bisbee Alice, Embury Stephen H, Farrer Lindsay A, Steinberg Martin H
Abstract excerpt
The complications of sickle cell disease are probably determined by genes whose products modify the pathophysiology initiated by the sickle haemoglobin mutation. Priapism, one vaso-occlusive manifestation of sickle cell disease, affects more than 30% of males with the disease. We examined the possible association of single nucleotide polymorphisms (SNPs) in 44 candidate genes of different functional classes for...
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