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Article

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families.

JAMA internal medicine - 1 Sept 2015

Kuo Chang-Fu, Grainge Matthew J, Valdes Ana M, See Lai-Chu, Luo Shue-Fen, Yu Kuang-Hui, Zhang Weiya, Doherty Michael

Abstract excerpt

IMPORTANCE: Relatives of patients with systemic lupus erythematosus (SLE) appear to be at higher risk of SLE and other autoimmune diseases, but estimates of individual familial risks are largely unavailable or unreliable. Furthermore, relative contributions of genetic, shared, and unshared environmental factors to SLE susceptibility remain unclear. OBJECTIVE: To examine familial aggregation and heritability of...

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Identifiers

PMID: 26193127
DOI: 10.1001/jamainternmed.2015.3528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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