Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-BDCA-4 (neuropilin-1) antibody can suppress virus-induced IFN-alpha production of plasmacytoid dendritic cells.

Immunology and cell biology - 1 Jul 2007

Grage-Griebenow Evelin, Löseke Stefan, Kauth Marion, Gehlhar Kirsten, Zawatzky Rainer, Bufe Albrecht

Abstract excerpt

Plasmacytoid dendritic cells (PDC) in human blood are the main source of virus-induced interferon (IFN)-alpha. They exhibit a lineage-negative phenotype but all express BDCA-4, which is homologous to the neuronal receptor neuropilin-1. Specific staining with anti-BDCA-4 antibody is used for posit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Cell Separation
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Interferon-gamma

Share to Neuropilin-1

Share to Transcription, Genetic

Share to Virus Attachment

Source

Identifiers

PMID: 17404592
DOI: 10.1038/sj.icb.7100048

Genes

PDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17404592-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-BDCA-4 (neuropilin-1) antibody can suppress virus-induced IFN-alpha production of plasmacytoid dendritic cells.PMID 17404592Read ↗

Flow cytometric techniques for studying plasmacytoid dendritic cells in mixed populations.Semantic proximity Read ↗

Purification of circulating plasmacytoid dendritic cells using counterflow centrifugal elutriation and immunomagnetic beads.Semantic proximity Read ↗

Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and functionSemantic proximity Read ↗

Functional characterization of ex vivo blood myeloid and plasmacytoid dendritic cells after infection with dengue virusSemantic proximity Read ↗

Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection.Semantic proximity Read ↗

Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16Semantic proximity Read ↗

Intravenous Immunoglobulin Therapy Restores the Quantity and Phenotype of Circulating Dendritic Cells and CD4+ T Cells in Children with Acute Kawasaki DiseaseSemantic proximity Read ↗

Cutting Edge: Antibody-Mediated TLR7-Dependent Recognition of Viral RNASemantic proximity Read ↗

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infectionsSemantic proximity Read ↗

Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis.Semantic proximity Read ↗

Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity.Semantic proximity Read ↗

The cell surface phenotype of human natural interferon-alpha producing cells as determined by flow cytometry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.