Article
Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2004
Lande Roberto, Giacomini Elena, Serafini Barbara, Rosicarelli Barbara, Sebastiani Gian Domenico, Minisola Giovanni, Tarantino Umberto, Riccieri Valeria, Valesini Guido, Coccia Eliana M
Abstract excerpt
Dendritic cells (DCs) are thought to play a key role in driving the immunopathogenic response underlying chronic inflammatory arthritis. In this study, we have examined the presence and phenotype of plasmacytoid DCs (pDCs) in the synovial fluids (SF) of patients with rheumatoid arthritis (RA), psoriatic arthritis (PA), and osteoarthritis (OA) and determined the chemotactic properties of SF from these patients...
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